The Church of Saint Nicholas Domenesque is an Orthodox church in Iai, built by Stefan cel Mare between 1491 and 1492, and rebuilt between 1884 and 1904 by the French architect André Lecomte du Noüy) by demolishing and rebuilding on the same foundation and preserving its original form. It is located in the city center near the old royal court between the Palace of Culture and Dosofti House, and was included in the list of historical monuments of Iai in 2015.